The Fort Payne Depot Museum (formerly the Alabama Great Southern Railroad Passenger Depot) is a historic building in Fort Payne, Alabama. The depot was built by the Alabama Great Southern Railroad in 1891, at the height of Fort Payne's mining-driven boom. Passenger service ended in 1970, but the depot continued to service freight until 1983. It was converted into a museum in 1986, which includes exhibits with 19th century and Native American artifacts, a collection of dioramas of fantasy scenes and historical events, and a former Norfolk Southern caboose.